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Series A Biotech Investors in the US

We've mapped 20 of the most active series a Biotech investors funding founders in the US, with cheques $25K–$500M.

Stages they backof 20 firms
  • Pre-seed7
  • Seed19
  • Series A20
  • Series B16
  • Series C+13
A firm counts at every stage it invests in.

We've mapped 20 of the most active series a Biotech investors funding founders in the US — 20 VCs. Cheque sizes across this segment run $25K–$500M.

When raising series a for a Biotech company in the US, founders should lead with the investors whose stage and cheque size actually match the round — not just the best-known names. 20 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.

VC
Verified Nov 2026

Amgen Ventures

Series A to B
🇺🇸US
BiotechHealthtech

Corporate venture arm of Amgen (since 2004); early-stage biotech investments in oncology, inflammation, neuroscience, cardiovascular. Sign in to see full profile →

VC
Verified Nov 2026
S.R. One logo

S.R. One

Seed to Series B
🇺🇸US
Biotech

Trans-Atlantic biotech venture capital firm (former GSK venture arm); offices in San Francisco and London; $600M Fund II. Sign in to see full profile →

VC
Verified Nov 2026
Deviation Capital logo

Deviation Capital

Seed to Series A
🇺🇸US
AI/MLBiotechCyber+7 more

Early-stage VC (Seed and Series A) backing technical founders building data- and compute-native companies; ~$2B AUM, offices in New York and San Francisco; e… Sign in to see full profile →

VC
Verified Nov 2026
Red Cedar Ventures logo

Red Cedar Ventures

Pre-seed to Series B
🇺🇸US
AI/MLBiotechClimate+3 more

Venture subsidiary of the MSU Research Foundation supporting early-stage high-tech startups emerging from Michigan State University. Sign in to see full profile →

VC
Verified Nov 2026
Emerald Development Manager logo

Emerald Development Manager

Seed to Series B
🇺🇸US
AI/MLBiotechClimate+4 more

New York-based early-stage VC backing elite scientific/engineering teams in cybersecurity/SaaS, biotech/healthcare IT, and clean tech/industrial tech. Sign in to see full profile →

VC
Verified May 2026
Hearst Ventures logo

Hearst Ventures

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechCyber+10 more

Corporate VC arm of Hearst Communications (since 1995) investing in media, information, and technology. Sign in to see full profile →

VC
Verified May 2026
11.2 Capital logo

11.2 Capital

Seed to Series A
🇺🇸US
AI/MLBiotechCyber+5 more

Early-stage VC investing in breakthrough deep tech: AI, cybersecurity, quantum, robotics, new space, bioengineering, climate. Sign in to see full profile →

VC
Verified Nov 2026
Andreessen Horowitz logo

Andreessen Horowitz

Seed to Series C+
🇺🇸US
AI/MLBiotechWeb3+2 moreGeneralist

Venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, with over $100B under management. Sign in to see full profile →

VC
Verified Nov 2026
Accel logo

Accel

Seed to Series C+
🇺🇸US
AI/MLConsumerCyber+7 moreGeneralist

Accel is a venture capital firm founded in 1983 and based in Palo Alto, with offices in San Francisco, London and India. Sign in to see full profile →

VC
Verified Nov 2026
General Catalyst logo

General Catalyst

Seed to Series C+
🇺🇸US
AI/MLBiotechClimate+10 more

Venture firm that creates new companies from scratch, partners with founders at seed and supports companies on a more enduring growth path, alongside a Custo… Sign in to see full profile →

VC
Verified Nov 2026
Khosla Ventures logo

Khosla Ventures

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechClimate+9 moreGeneralist

Khosla Ventures is a Menlo Park, California venture capital firm founded in 2004 by Vinod Khosla. Sign in to see full profile →

VC
Verified Nov 2026
Menlo Ventures logo

Menlo Ventures

Seed to Series C+
🇺🇸US
AI/MLBiotechConsumer+5 more

Menlo Park-based VC, founded in 1976, investing heavily in AI across software verticals, alongside bio and healthcare, consumer, cybersecurity, defence, fint… Sign in to see full profile →

VC
Verified Nov 2026
First Round Capital logo

First Round Capital

Pre-seed to Series A
🇺🇸US
AI/MLClimateConsumer+7 moreGeneralist

First Round Capital is a US seed-stage venture firm founded in 2004 by Josh Kopelman and Howard Morgan, with offices in San Francisco (HQ), New York and Phil… Sign in to see full profile →

VC
Verified Nov 2026
Bessemer Venture Partners logo

Bessemer Venture Partners

Seed to Series C+
🇺🇸US
AI/MLBiotechConsumer+7 more

Bessemer Venture Partners is a US-headquartered multi-stage venture capital firm investing globally from seed through growth across cloud/SaaS, AI & ML, cybe… Sign in to see full profile →

VC
Verified Nov 2026
Alumni Ventures logo

Alumni Ventures

Pre-seed · Seed · Series A, C+
🇺🇸US
AI/MLBiotechClimate+6 more

Alumni Ventures is a Manchester, New Hampshire venture capital firm that gives individual accredited investors access to venture and late-stage private inves… Sign in to see full profile →

VC
Verified Nov 2026
8VC logo

8VC

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechClimate+7 more

8VC is an Austin, Texas technology investment firm founded in 2015 by Joe Lonsdale after the wind-down of Formation 8. Sign in to see full profile →

VC
Verified Nov 2026
Kleiner Perkins logo

Kleiner Perkins

Seed to Series C+
🇺🇸US
AI/MLBiotechClimate+6 more

Kleiner Perkins is a Menlo Park venture capital firm, founded in 1972, that invests in seed, early-stage and growth companies. Sign in to see full profile →

VC
Verified Nov 2026
GV logo

GV

Seed to Series C+
🇺🇸US
AI/MLBiotechClimate+10 more

GV (formerly Google Ventures) is the venture capital arm of Alphabet, founded in 2009 and headquartered in Mountain View with offices in San Francisco, Cambr… Sign in to see full profile →

VC
Verified Nov 2026
Lux Capital logo

Lux Capital

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechClimate+7 more

Lux Capital is a New York-based science and tech VC (founded 2000 by Peter Hebert, Robert Paull, and Josh Wolfe) with $7B+ AUM. Sign in to see full profile →

VC
Verified Nov 2026
NEA logo

NEA

Seed to Series C+
🇺🇸US
AI/MLBiotechClimate+6 more

NEA (New Enterprise Associates) is a venture capital firm founded in 1977 and headquartered in Menlo Park, California, with offices in New York, Timonium and… Sign in to see full profile →

Directory last updated: November 2026.

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