MatchFund

Series A B2B SaaS Investors in the US

We've mapped 20 of the most active series a B2B SaaS investors funding founders in the US, with cheques $100Kโ€“$500M.

Stages they backof 20 firms
  • Pre-seed7
  • Seed20
  • Series A20
  • Series B17
  • Series C+13
A firm counts at every stage it invests in.

We've mapped 20 of the most active series a B2B SaaS investors funding founders in the US โ€” 20 VCs. Cheque sizes across this segment run $100Kโ€“$500M.

When raising series a for a B2B SaaS company in the US, founders should lead with the investors whose stage and cheque size actually match the round โ€” not just the best-known names. 20 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.

VC
Verified Nov 2026
M12 logo

M12

Seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLCyberDeeptech+3 more

Microsoft's venture capital fund, investing in seed through Series B companies in AI apps, security for AI, AI cloud infrastructure, AI data ops and models, โ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Greenoaks logo

Greenoaks

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLConsumerSaaS+3 more

Greenoaks is a San Francisco investment firm, founded in 2012 by Neil Mehta and Benny Peretz, that makes concentrated, long-term investments in technology-enโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
IBM Ventures logo

IBM Ventures

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateCyber+2 more

IBM's $500M+ corporate venture arm backing early-stage AI, quantum, security, data, sustainability startups. Sign in to see full profile โ†’

VC
Verified Nov 2026
Streamlined Ventures logo

Streamlined Ventures

Pre-seed to Series A
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLWeb3SaaS+4 more

Palo Alto-based solo-GP seed VC (founded 2013 by Ullas Naik) backing software companies in AI, data science, automation, APIs, blockchain and gaming. Sign in to see full profile โ†’

VC
Verified Nov 2026
Citi Ventures logo

Citi Ventures

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLWeb3Cyber+3 more

Citi's venture arm, investing in and partnering with startups transforming financial services, from seed to Series F and beyond, across fintech, AI and data,โ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Deviation Capital logo

Deviation Capital

Seed to Series A
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechCyber+7 more

Early-stage VC (Seed and Series A) backing technical founders building data- and compute-native companies; ~$2B AUM, offices in New York and San Francisco; eโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Valar Ventures logo

Valar Ventures

Pre-seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
SaaSFintech

Manhattan-based VC co-founded by Peter Thiel, Andrew McCormack and James Fitzgerald in 2010; focuses on international fintech outside Silicon Valley (Wise, Nโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Emerald Development Manager logo

Emerald Development Manager

Seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+4 more

New York-based early-stage VC backing elite scientific/engineering teams in cybersecurity/SaaS, biotech/healthcare IT, and clean tech/industrial tech. Sign in to see full profile โ†’

VC
Verified May 2026
Applied Ventures logo

Applied Ventures

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateDeeptech+5 more

Applied Ventures is the corporate venture capital arm of Applied Materials (NASDAQ: AMAT), founded 2006 and based in Santa Clara, CA. Sign in to see full profile โ†’

VC
Verified May 2026
Hearst Ventures logo

Hearst Ventures

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechCyber+10 more

Corporate VC arm of Hearst Communications (since 1995) investing in media, information, and technology. Sign in to see full profile โ†’

VC
Verified May 2026
Leawood Venture Capital logo

Leawood Venture Capital

Pre-seed to Series B
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLCyberSaaS+3 more

Leawood Kansas-based early-stage VC investing in technology companies across the US since 2017. Sign in to see full profile โ†’

VC
Verified Nov 2026
Andreessen Horowitz logo

Andreessen Horowitz

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechWeb3+2 moreGeneralist

Venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, with over $100B under management. Sign in to see full profile โ†’

VC
Verified Nov 2026
Accel logo

Accel

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLConsumerCyber+7 moreGeneralist

Accel is a venture capital firm founded in 1983 and based in Palo Alto, with offices in San Francisco, London and India. Sign in to see full profile โ†’

VC
Verified Nov 2026
Sequoia Capital logo

Sequoia Capital

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateConsumer+5 more

VC firm that partners with founders early, sometimes when a company is no more than an idea, and helps them build companies from idea to IPO and beyond. Sign in to see full profile โ†’

VC
Verified Nov 2026
Lightspeed Venture Partners logo

Lightspeed Venture Partners

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLConsumerCyber+5 more

Lightspeed Venture Partners is a global, multi-stage venture capital firm headquartered in Menlo Park, California, investing from seed through growth and latโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
General Catalyst logo

General Catalyst

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+10 more

Venture firm that creates new companies from scratch, partners with founders at seed and supports companies on a more enduring growth path, alongside a Custoโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
Insight Partners logo

Insight Partners

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLCyberSaaS+3 more

Global software-focused VC/PE firm (rebranded from Insight Venture Partners) with >$90B AUM; backs scaling software and internet companies worldwide. Sign in to see full profile โ†’

VC
Verified Nov 2026
Khosla Ventures logo

Khosla Ventures

Pre-seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechClimate+9 moreGeneralist

Khosla Ventures is a Menlo Park, California venture capital firm founded in 2004 by Vinod Khosla. Sign in to see full profile โ†’

VC
Verified Nov 2026
Menlo Ventures logo

Menlo Ventures

Seed to Series C+
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLBiotechConsumer+5 more

Menlo Park-based VC, founded in 1976, investing heavily in AI across software verticals, alongside bio and healthcare, consumer, cybersecurity, defence, fintโ€ฆ Sign in to see full profile โ†’

VC
Verified Nov 2026
First Round Capital logo

First Round Capital

Pre-seed to Series A
๐Ÿ‡บ๐Ÿ‡ธUS
AI/MLClimateConsumer+7 moreGeneralist

First Round Capital is a US seed-stage venture firm founded in 2004 by Josh Kopelman and Howard Morgan, with offices in San Francisco (HQ), New York and Philโ€ฆ Sign in to see full profile โ†’

Directory last updated: November 2026.

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