MatchFund

Seed Deeptech Investors in the US

We've mapped 20 of the most active seed Deeptech investors funding founders in the US, with cheques $100K–$100M.

We've mapped 20 of the most active seed Deeptech investors funding founders in the US — 20 VCs. Cheque sizes across this segment run $100K–$100M.

When raising seed for a Deeptech company in the US, founders should lead with the investors whose stage and cheque size actually match the round — not just the best-known names. 20 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.

VC
Verified May 2026
IBM Ventures logo

IBM Ventures

Seed · Series A · Series B · Later
🇺🇸US
AI/MLClimateCyber+2 more

IBM's $500M+ corporate venture arm backing early-stage AI, quantum, security, data, sustainability startups. Sign in to see full profile →

VC
Verified May 2026
Applied Ventures logo

Applied Ventures

Pre-seed · Seed · Series A · Series B · Later
🇺🇸US
AI/MLClimateDeeptech+5 more

Applied Ventures is the corporate venture capital arm of Applied Materials (NASDAQ: AMAT), founded 2006 and based in Santa Clara, CA. Sign in to see full profile →

VC
Verified May 2026
11.2 Capital logo

11.2 Capital

Seed · Series A
🇺🇸US
AI/MLBiotechCyber+5 more

Early-stage VC investing in breakthrough deep tech: AI, cybersecurity, quantum, robotics, new space, bioengineering, climate. Sign in to see full profile →

VC
Verified May 2026
Foothill Ventures logo

Foothill Ventures

Pre-seed · Seed · Series A
🇺🇸US
AI/MLBiotechCyber+5 more

Silicon Valley seed-stage deep-tech VC (rebranded from Tsingyuan Ventures to Foothill Ventures in 2021); invests in software, life science and frontier hard … Sign in to see full profile →

VC
Verified May 2026
M12 logo

M12

Seed · Series A · Series B · Later
🇺🇸US
AI/MLCyberDeeptech+3 more

Invests in: Europe, Israel, USA Sign in to see full profile →

VC
Verified Sep 2026
Robin Hood Ventures logo

Robin Hood Ventures

Seed · Series A
🇺🇸US
AI/MLAR/VRBiotech+13 moreGeneralist

Robin Hood Ventures is a Philadelphia-based angel investment group founded in 1999, made up of experienced entrepreneurs and accredited investors who back ea… Sign in to see full profile →

VC
Verified Sep 2026
Unshackled Ventures logo

Unshackled Ventures

Pre-seed · Seed
🇺🇸US
AI/MLBiotechClimate+5 moreGeneralist

Pre-seed VC (Palo Alto, founded 2015 by Manan Mehta and Nitin Pachisia) backing immigrant founders with capital, immigration support and conviction at pre-pr… Sign in to see full profile →

VC
Verified Sep 2026
AlleyCorp logo

AlleyCorp

Pre-seed · Seed
🇺🇸US
ConsumerEdTechHealthtech+1 moreGeneralist

Looking at companies from the idea stage to 50K+ in MRR We are tech pioneers, investors, and entrepreneurs. We build and invest in transformative companies Sign in to see full profile →

VC
Verified Sep 2026
Anzu Partners logo

Anzu Partners

Pre-seed · Seed · Series A · Series B
🇺🇸US
AI/MLBiotechClimate+4 more

Invests in: Europe, Israel, USA, Canada, Asia, Worldwide We are an investment firm that focuses on early stage companies with breakthrough industrial & life … Sign in to see full profile →

VC
Verified Sep 2026
Cottonwood Technology Fund logo

Cottonwood Technology Fund

Pre-seed · Seed · Series A · Series B
🇺🇸US
ClimateDeeptechHealthtech+3 more

Cottonwood Technology Fund is an early stage venture capital fund that makes impact investments in Key Enabling Technologies (Deep Tech & Hard Science). Sign in to see full profile →

VC
Verified Sep 2026
Cowboy Ventures logo

Cowboy Ventures

Pre-seed · Seed
🇺🇸US
AR/VRConsumerCyber+7 moreGeneralist

Co-Invest — Looking at companies from the idea stage to those that have shown product-market fit Sign in to see full profile →

VC
Verified Sep 2026
Fifty Years logo

Fifty Years

Pre-seed · Seed
🇺🇸US
AI/MLBiotechClimate+5 moreGeneralist

Lead, Co-Invest — Looking at companies from the idea stage to 500K+ in MRR Sign in to see full profile →

VC
Verified Sep 2026
Future Ventures logo

Future Ventures

Pre-seed · Seed · Series A · Series B
🇺🇸US
AI/MLBiotechClimate+10 moreGeneralist

Future Ventures is a US venture capital firm founded in 2018 by Steve Jurvetson and Maryanna Saenko that invests at seed and early stage in mission-driven fr… Sign in to see full profile →

VC
Verified Sep 2026
Harlem Capital logo

Harlem Capital

Pre-seed · Seed
🇺🇸US
ConsumerFintechHealthtech+1 moreGeneralist

Lead — Looking at companies that have shown product-market fit Harlem Capital is a venture capital firm that backs the next generation of winners. Sign in to see full profile →

VC
Verified Sep 2026
Incite logo

Incite

Seed · Series A
🇺🇸US
ClimateDeeptechEdTech

Incite.org is a Burlingame, California-based mission-driven investment platform founded by Matt Rogers (co-founder of Nest and Mill) and Swati Mylavarapu. Sign in to see full profile →

VC
Verified Sep 2026
Khosla Ventures logo

Khosla Ventures

Pre-seed · Seed · Series A · Series B · Later
🇺🇸US
AI/MLBiotechClimate+9 moreGeneralist

Khosla Ventures is a Menlo Park, California venture capital firm founded in 2004 by Vinod Khosla. Sign in to see full profile →

VC
Verified Sep 2026
Material Impact Fund logo

Material Impact Fund

Seed · Series A · Series B
🇺🇸US
BiotechClimateDeeptech+4 more

Invests in: USA Material Impact is a champion of the bravest ideas for the future, building companies from the ground up that turn material science and deep… Sign in to see full profile →

VC
Verified Sep 2026
Prelude Ventures logo

Prelude Ventures

Pre-seed · Seed · Series A · Series B · Later
🇺🇸US
AI/MLBiotechClimate+7 more

Invests in: USA Prelude Ventures invests in and supports early-stage startups with the greatest potential to mitigate climate change. Sign in to see full profile →

VC
Verified May 2026
Sutter Hill Ventures logo

Sutter Hill Ventures

Seed · Series A · Series B
🇺🇸US
DeeptechSaaSFintech+2 more

Sutter Hill Ventures is a Palo Alto, California venture capital firm founded in 1962 by Bill Draper and Paul Wythes. Sign in to see full profile →

VC
Verified May 2026
Scout Ventures logo

Scout Ventures

Pre-seed · Seed · Series A
🇺🇸US
AI/MLClimateCyber+4 more

Invests in: USA, Canada Sign in to see full profile →

Looking for the right investors for your specific company? MatchFund ranks every investor against your profile, sector, stage, and traction — not just the obvious ones.

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Directory last updated: September 2026