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Pre-seed AI Investors in the US

We've mapped 20 of the most active pre-seed AI investors funding founders in the US, with cheques $25K–$100M.

Stages they backof 20 firms
  • Pre-seed20
  • Seed20
  • Series A19
  • Series B12
  • Series C+9
A firm counts at every stage it invests in.

We've mapped 20 of the most active pre-seed AI investors funding founders in the US — 20 VCs. Cheque sizes across this segment run $25K–$100M.

When raising pre-seed for a AI company in the US, founders should lead with the investors whose stage and cheque size actually match the round — not just the best-known names. 20 of these profiles have been verified in the last review pass. Sign in to see each investor's full thesis, cheque range, and how closely they fit your specific company.

VC
Verified Sep 2026
TTV Capital logo

TTV Capital

Pre-seed to Series A
🇺🇸US
AI/MLWeb3Cyber+1 more

Atlanta-based fintech VC (founded 2000); invests in financial services and financial-product companies serving the sector and consumers. Sign in to see full profile →

VC
Verified Sep 2026
Streamlined Ventures logo

Streamlined Ventures

Pre-seed to Series A
🇺🇸US
AI/MLWeb3SaaS+4 more

Palo Alto-based solo-GP seed VC (founded 2013 by Ullas Naik) backing software companies in AI, data science, automation, APIs, blockchain and gaming. Sign in to see full profile →

VC
Verified Sep 2026
Red Cedar Ventures logo

Red Cedar Ventures

Pre-seed to Series B
🇺🇸US
AI/MLBiotechClimate+3 more

Venture subsidiary of the MSU Research Foundation supporting early-stage high-tech startups emerging from Michigan State University. Sign in to see full profile →

VC
Verified May 2026
Hearst Ventures logo

Hearst Ventures

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechCyber+10 more

Corporate VC arm of Hearst Communications (since 1995) investing in media, information, and technology. Sign in to see full profile →

VC
Verified May 2026
Leawood Venture Capital logo

Leawood Venture Capital

Pre-seed to Series B
🇺🇸US
AI/MLCyberSaaS+3 more

Leawood Kansas-based early-stage VC investing in technology companies across the US since 2017. Sign in to see full profile →

VC
Verified May 2026
Applied Ventures logo

Applied Ventures

Pre-seed to Series C+
🇺🇸US
AI/MLClimateDeeptech+5 more

Applied Ventures is the corporate venture capital arm of Applied Materials (NASDAQ: AMAT), founded 2006 and based in Santa Clara, CA. Sign in to see full profile →

VC
Verified Sep 2026
Eclipse logo

Eclipse

Pre-seed to Series C+
🇺🇸US
AI/MLClimateCyber+5 more

Palo Alto VC with $2B+ AUM investing in physical-economy startups: manufacturing, logistics, supply chain, energy, defense, robotics. Sign in to see full profile →

VC
Verified Sep 2026
First Round Capital logo

First Round Capital

Pre-seed to Series A
🇺🇸US
AI/MLClimateConsumer+7 moreGeneralist

First Round Capital is a US seed-stage venture firm founded in 2004 by Josh Kopelman and Howard Morgan, with offices in San Francisco (HQ), New York and Phil… Sign in to see full profile →

VC
Verified Sep 2026
Khosla Ventures logo

Khosla Ventures

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechClimate+9 moreGeneralist

Khosla Ventures is a Menlo Park, California venture capital firm founded in 2004 by Vinod Khosla. Sign in to see full profile →

VC
Verified Sep 2026
FirstMark Capital logo

FirstMark Capital

Pre-seed to Series B
🇺🇸US
AI/MLConsumerFintech+1 more

Early-stage venture capital firm based in New York City that backs exceptional founders and supports them through a platform of networks, talent recruiting, … Sign in to see full profile →

VC
Verified Sep 2026
Alumni Ventures logo

Alumni Ventures

Pre-seed · Seed · Series A, C+
🇺🇸US
AI/MLBiotechClimate+6 more

Alumni Ventures is a Manchester, New Hampshire venture capital firm that gives individual accredited investors access to venture and late-stage private inves… Sign in to see full profile →

VC
Verified Sep 2026
Spark Capital logo

Spark Capital

Pre-seed to Series C+
🇺🇸US
AI/MLClimateConsumer+7 more

Invests in: Europe, Israel, USA, Canada, Asia, Worldwide VC firm investing and partnering with world-changing in companies. Sign in to see full profile →

VC
Verified Sep 2026
Kindred Ventures logo

Kindred Ventures

Pre-seed to Series B
🇺🇸US
AI/MLClimateConsumer+4 more

Kindred Ventures is a San Francisco venture capital firm that invests at the earliest stages in founders building with technology and science, across AI, cry… Sign in to see full profile →

VC
Verified Sep 2026
SOSV logo

SOSV

Pre-seed to Series A
🇺🇸US
AI/MLBiotechClimate+5 more

SOSV is a multi-stage venture capital firm investing in deep tech for human and planetary health, from physical AI and hard tech to therapeutics, energy and … Sign in to see full profile →

VC
Verified Sep 2026
Greylock logo

Greylock

Pre-seed to Series C+
🇺🇸US
AI/MLConsumerWeb3+8 more

Greylock is a venture capital firm founded in 1965 and headquartered in Menlo Park, California, that focuses on early-stage companies; most of its investment… Sign in to see full profile →

VC
Verified Sep 2026
8VC logo

8VC

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechClimate+7 more

8VC is an Austin, Texas technology investment firm founded in 2015 by Joe Lonsdale after the wind-down of Formation 8. Sign in to see full profile →

VC
Verified Sep 2026
Coinbase Ventures logo

Coinbase Ventures

Pre-seed to Series A
🇺🇸US
AI/MLWeb3Fintech+2 more

Coinbase Ventures invests in exceptional founders who share Coinbase’s mission of creating more economic freedom for the world. Sign in to see full profile →

VC
Verified Sep 2026
Lux Capital logo

Lux Capital

Pre-seed to Series C+
🇺🇸US
AI/MLBiotechClimate+7 more

Lux Capital is a New York-based science and tech VC (founded 2000 by Peter Hebert, Robert Paull, and Josh Wolfe) with $7B+ AUM. Sign in to see full profile →

VC
Verified Sep 2026
AlleyCorp logo

AlleyCorp

Pre-seed to Seed
🇺🇸US
ConsumerEdTechHealthtech+1 moreGeneralist

Looking at companies from the idea stage to 50K+ in MRR We are tech pioneers, investors, and entrepreneurs. We build and invest in transformative companies Sign in to see full profile →

VC
Verified Sep 2026
BoxGroup logo

BoxGroup

Pre-seed to Series A
🇺🇸US
AI/MLBiotechClimate+6 more

Investor built in NYC and SF backing founders at the earliest stage, from pre-seed to as late as Series A, with cheques of up to $1M and companies funded any… Sign in to see full profile →

Directory last updated: September 2026.

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